Pharmacokinetics, efficacy and convulsive dose of articaine hydrochloride in goat kids
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چکیده
منابع مشابه
A Clinical Study of Efficacy of 4% Articaine Hydrochloride Versus 2% Lignocaine Hydrochloride in Dentistry
BACKGROUND Articaine in an anesthetic agent, which is used less frequently in dentistry. It differs from other agents due to the presence of a thiophene ring in its molecular structure. Few groups of researchers claim that it is superior to lignocaine. Hence, the purpose of this study was to compare the efficacy of 4% articaine hydrochloride and 2% lignocaine hydrochloride in the orthodontic ex...
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The single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride were compared in a randomized, two-period, crossover study involving six young (less than or equal to 35 years) and six elderly (less than or equal to 60 years) adults. Subjects ingested single 200-mg oral doses after an overnight fast, and serial plasma (0 to 96 h), nasal mucus (0 to 8 h), and urine (0 t...
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BACKGROUND High dose oral thiamine may have a role in treating diabetes, heart failure, and hypermetabolic states. The purpose of this study was to determine the pharmacokinetic profile of oral thiamine hydrochloride at 100 mg, 500 mg and 1500 mg doses in healthy subjects. METHODS This was a randomized, double-blind, single-dose, 4-way crossover study. Pharmacokinetic measures were calculated...
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Tetracycline may be used to treat several types of bacterial diseases in ruminants. In addition, tetracycline is added to food to promote the growth. There are few reports on the pharmacokinetics of tetracycline in sheep. Therefore, the objective of this study was to examine the pharmacokinetic characteristics of the drug in sheep. Ten apparently healthy mixed-breed sheep were administered 20 m...
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Complex pharmacokinetic (PK) properties including nonlinear elimination were encountered by some monoclonal antibodies (mAbs), and classic compartment models sometimes failed to appropriately describe those properties. In this work, a new model was built on a comprehensive analysis of the complex elimination of mAbs. This new model was firstly utilized to fit with the single-dose plasma concent...
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ژورنال
عنوان ژورنال: Veterinary Anaesthesia and Analgesia
سال: 2021
ISSN: 1467-2987
DOI: 10.1016/j.vaa.2019.12.012